Eshraghi Lab

Khalid N and Eshraghi A. High-Throughput Profiling of Bacterial Respiration Using the Resipher Reveals Functional Responses to Nutrients and Antibiotics. Frontiers in Microbiology. 2026 Jul 24:17:1849812 https://doi.org/10.3389/fmicb.2026.1849812 (PMID 42569245)
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Khalid N, Van Horn C, Li D, Ostrov D, and Eshraghi A. Selective inhibition of respiratory complex I reveals a bioenergetic vulnerability in Francisella. (In review and deposited as a preprint to BioRxiv). 6/5/2026 https://doi.org/10.64898/2026.06.04.730185 (PMID 42282675)​


Eshraghi A and Logsden LK. Sustained Improvements in Student Outcomes Following Integration of Clinical Case Narratives in Veterinary Microbiology Curriculum. (In review and deposited as a preprint to BioRxiv). 6/1/2026 https://doi.org/10.64898/2026.05.22.727235 (PMID 42282533)


Ramos LA, Actis LA, Penwell WF, Eshraghi A and S.E. Fiester. Coordinated Virulence in Acinetobacter baumannii: Mechanisms, Integration, and Therapeutic Opportunities. 2026 (In review)
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Van Horn C, Khalid N, Heine HS, and Eshraghi A. Tolfenpyrad modulates antibiotic activity on Francisella novicida and synergizes with electron transport chain inhibitors. ACS Infectious Diseases. 2026. May 8; 12 (5), 1704-1716 https://doi.org/10.1021/acsinfecdis.6c00066. (PMID 41979023)
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Jones KL, Adams N, Lundgren AM, Irvin A, Eshraghi A. The microdrip method rapidly and efficiently enumerates bacterial colony-forming units in bovine milk.  Journal of Dairy Science Communications. 2025. Jul 30;6(6):816-821. DOI: 10.3168/jdsc.2025-0788. eCollection 2025 Nov. (PMID 41220993)
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Santelices J, Schultz, A, Walker A, Adams N, Tirado D, Barker H, Eshraghi A, Czyz D, Ferraro MJ. Targeting deubiquitinating enzymes and ubiquitin pathway modulators to enhance host defense against bacterial infections. mBio. 2025 Sep 3;:e0031225. DOI: 10.1128/mbio.00312-25. (PMID 40899844)


Adams N, Hulvey D, Khalid N, Burne A, Brown MB, and Eshraghi A. Pathogenicity determinant protein E is a Francisella type VI secretion system effector protein that modulates host death. BioRxiv (preprint) https://doi.org/10.1101/2024.11.25.624902


Khalid N, Adams N, Cunha F, Taki AC, Le TG, Baell JB, Heine HS, Gasser RB, Eshraghi A. Tolfenpyrad Derivatives Exhibit Potent Francisella-Specific Antibacterial Activity without Toxicity to Mammalian Cells In Vitro. ACS Infect Diseases. 2024 Nov 8;10(11):3902-3914;
https://doi.org/10.1021/acsinfecdis.4c00547. (PMID 39356820)


Clarke A, Llabona IM, Khalid N, Hulvey D, Irvin A, Adams N, Heine HS, Eshraghi A. Tolfenpyrad displays Francisella-targeted antibiotic activity that requires an oxidative stress response regulator for sensitivity. Microbiology Spectrum. 2023 Dec 12;11(6):e0271323. https://doi.org/10.1128/spectrum.02713-23 (PMID: 37800934)
 

Ghasemieshkaftaki M, Vasquez I, , Gamperl AK, Santander J. Comparative Genomic Analysis of a Novel Vibrio sp. Isolated from an Ulcer Disease Event in Atlantic Salmon (Salmo salar). Microorganisms. 2023 Jul 2;11(7). https://doi.org/10.3390/microorganisms11071736. (PMID: 37512908)
 

Ledvina HE, Kelly KA, Eshraghi A, Plemel RL, Peterson SB, Lee B, Steele S, Adler M, Kawula TH, Merz AJ, Skerrett SJ, Celli J, Mougous JD. A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of Francisella. Cell Host & Microbe. 2018. Aug 8;24(2):285-295.e8. DOI: 10.1016/j.chom.2018.07.003


Eshraghi A, Kim J, Walls AC, Ledvina HE, Miller CN, Ramsey KM, Whitney JC, Radey MC, Peterson SB, Ruhland BR, Tran BQ, Goo YA, Goodlett DR, Dove SL, Celli J, Veesler D, Mougous JD. Secreted Effectors Encoded within and outside of the Francisella Pathogenicity Island Promote Intramacrophage Growth. Cell Host & Microbe. 2016. Nov 9;20(5):573-583. DOI: 10.1016/j.chom.2016.10.008.


Dixon SD, Huynh MM, Tamilselvam B, Spiegelman LM, Son SB, Eshraghi A, Blanke SR, Bradley KA. Distinct Roles for CdtA and CdtC during Intoxication by Cytolethal Distending Toxins. PLoS One. 2015. Nov 30;10(11):e0143977. DOI: 10.1371/journal.pone.0143977.


Eshraghi A, Dixon SD, Tamilselvam B, Kim EJ, Gargi A, Kulik JC, Damoiseaux R, Blanke SR, Bradley KA. Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry. PLoS Pathogens. 2014. Jul 31;10(7):e1004295.  DOI: 10.1371/journal.ppat.1004295.


Gargi A, Tamilselvam B, Powers B, Prouty MG, Lincecum T, Eshraghi A, Maldonado-Arocho FJ, Wilson BA, Bradley KA, Blanke SR. Cellular interactions of the cytolethal distending toxins from Escherichia coli and Haemophilus ducreyi. Journal of Biological Chemistry. 2013. Mar 15;288(11):7492-7505.  DOI: 10.1074/jbc.M112.448118.


Eshraghi A, Maldonado-Arocho FJ, Gargi A, Cardwell MM, Prouty MG, Blanke SR, Bradley KA. Cytolethal distending toxin family members are differentially affected by alterations in host glycans and membrane cholesterol. Journal of Biological Chemistry. 2010. Jun 11;285(24):18199-207.  DOI: 10.1074/jbc.M110.112912.