Eshraghi Lab

Adams N, Hulvey D, Khalid N, Burne A, Brown MB, and Eshraghi A. Pathogenicity determinant protein E is a Francisella type VI secretion system effector protein that modulates host death. BioRxiv (preprint) https://doi.org/10.1101/2024.11.25.624902


Khalid N, Adams N, Cunha F, Taki AC, Le TG, Baell JB, Heine HS, Gasser RB, Eshraghi A. Tolfenpyrad Derivatives Exhibit Potent Francisella-Specific Antibacterial Activity without Toxicity to Mammalian Cells In Vitro. ACS Infect Dis. 2024 Oct 2;. doi: 10.1021/acsinfecdis.4c00547. [Epub ahead of print] PubMed PMID: 39356820.


Clarke A, Llabona IM, Khalid N, Hulvey D, Irvin A, Adams N, Heine HS, Eshraghi A. Tolfenpyrad displays Francisella-targeted antibiotic activity that requires an oxidative stress response regulator for sensitivity. Microbiology Spectrum. 2023 Oct 6;:e0271323. doi: 10.1128/spectrum.02713-23. [Epub ahead of print] PubMed PMID: 37800934.
 

Ghasemieshkaftaki M, Vasquez I, , Gamperl AK, Santander J. Comparative Genomic Analysis of a Novel Vibrio sp. Isolated from an Ulcer Disease Event in Atlantic Salmon (Salmo salar). Microorganisms. 2023 Jul 2;11(7). doi: 10.3390/microorganisms11071736. PubMed PMID: 37512908; PubMed Central PMCID: PMC10385127.
 

Ledvina HE, Kelly KA, Eshraghi A, Plemel RL, Peterson SB, Lee B, Steele S, Adler M, Kawula TH, Merz AJ, Skerrett SJ, Celli J, Mougous JD. A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of Francisella. Cell Host & Microbe. 2018


Eshraghi A, Kim J, Walls AC, Ledvina HE, Miller CN, Ramsey KM, Whitney JC, Radey MC, Peterson SB, Ruhland BR, Tran BQ, Goo YA, Goodlett DR, Dove SL, Celli J, Veesler D, Mougous JD. Secreted Effectors Encoded within and outside of the Francisella Pathogenicity Island Promote Intramacrophage Growth. Cell Host & Microbe. 2016


Dixon SD, Huynh MM, Tamilselvam B, Spiegelman LM, Son SB, Eshraghi A, Blanke SR, Bradley KA. Distinct Roles for CdtA and CdtC during Intoxication by Cytolethal Distending Toxins. PLoS One. 2015


Eshraghi A, Dixon SD, Tamilselvam B, Kim EJ, Gargi A, Kulik JC, Damoiseaux R, Blanke SR, Bradley KA. Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry. PLoS Pathogens. 2014


Gargi A, Tamilselvam B, Powers B, Prouty MG, Lincecum T, Eshraghi A, Maldonado-Arocho FJ, Wilson BA, Bradley KA, Blanke SR. Cellular interactions of the cytolethal distending toxins from Escherichia coli and Haemophilus ducreyi. Journal of Biological Chemistry. 2013


Eshraghi A, Maldonado-Arocho FJ, Gargi A, Cardwell MM, Prouty MG, Blanke SR, Bradley KA. Cytolethal distending toxin family members are differentially affected by alterations in host glycans and membrane cholesterol. Journal of Biological Chemistry. 2010